The only way to access it is by clicking the cube, or Zoltun Kulle standing beside it in town.

Click it and it will return to town and can be used indefinitely on non-Season characters. Make your way through the Elder Sanctum until you find it.

The Cube is typically found in the Elder Sanctum which is located in the top right, lower left or right of the Ruins of Sescheron. To find Kanai’s Cube, obtain it from the Ruins of Sescheron (Act 3) in Adventure Mode. Kanai’s Cube Location and how to use itįirst of all you need to find Kanai’s Cube.Finaly, turn to the page that lists the extracted powers and equip the one you want. Click on the right cube slot (weapon, armor, or jewelry). Click the Transmute button and you will extract the power from the item. Right-click the specific item in your inventory you wish to extract the power from. Click the Fill button to add the appropriate materials, which are the following: the item you will extract the power from, 1 Khanduran Rune, 1 Caldeum Nightshade, 1 Arreat War Tapestry, 1 Corrupted Angel Flex, 1 Westmarch Holy Water, and 5 Death’s Breath. Go to page 1 where you will find the Archive of Tal Rasha, which is the recipe for extracting power. To extract legendary power, acces Kanai’s Cube and click on the Recipe button to the right of the Transmute button. You will be able to complete several Horadric rituals with it, including the extraction of legendary power. The spirit will point you towards the location of the Cube. You will need to speak with the spirit of Zoltun Kulle. You will obtain by starting a game in Adventure Mode and heading to any town in any act. In order to extract legendary power, you will first need to get the Kanai’s Cube.

Diablo 3 kanai's cube powers